Background: The negative pressure pulmonary edema is rare clinical situation which caused mainly by upper\nairway obstruction. However except upper airway obstruction, there may be other pathophysiological disorders\nmaking patients more vulnerable to pulmonary edema. Based on these disorders, upper airway obstruction is the\ntrigger to induce negative pressure pulmonary edema.\nCase presentation: This case was a 5-year-old girl with tumor on saddle area, her hormones level were abnormal\npreoperatively, such as cortisol, adrenocorticotrophic hormone, free T4 and total T4. During the stage of induction,\nnegative pressure pulmonary edema took place due to mild upper airway obstruction. And the instant chest\nComputer tomography proved diagnosis clue. After intensive care, most lung field of this girl recovered to normal\nwithin 48 h.\nConclusion: The patient with abnormal hormone levels is vulnerable to pulmonary edema, mild upper airway\nobstruction triggered negative pressure pulmonary. Thus pre-operation hormones supplement is as important as\nkeeping upper airway unobstructed.
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